Posted on February 24, 2009

Weight loss reduced frequency of urinary incontinence

In addition to prevention of diabetes, decreased urinary incontinence may be an additional benefit of weight loss.

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Behavioral intervention targeting weight loss reduced self-reported urinary incontinence episodes in overweight and obese women compared with a structured education program.

The researchers randomly assigned overweight and obese women with at least 10 urinary-incontinence episodes per week to either a six-month weight-loss program including diet, exercise and behavior modification (n=226), or to a structured education program (n=112). The mean age of participants was 53 years.

Incontinence decreased

The mean weight loss was 8% in the intervention group compared with 1.6% in the control group (P<.001). The mean weekly number of episodes decreased by 47% in the intervention group vs. the control group (28%; P=.01). The intervention group had a greater reduction in frequency of stress-incontinence episodes (P=.02) but not of urge-incontinence episodes (P=.14) as compared with the control group.

A higher proportion of the intervention group had a reduction of ≥70% in frequency of all incontinence episodes (P<.001), stress-incontinence episodes (P=.009) and urge-incontinence episodes (P=.04) vs. the control group, according to the study.

“A decrease in urinary incontinence is another health benefit associated with weight loss, and that weight reduction can be a first-line treatment in overweight and obese women,” Leslee L. Subak, MD, obstetrician/gynecologist at the University of California, San Francisco, said in a press release. – by Christen Haigh

N Engl J Med. 2009;360:481-490.

PERSPECTIVE

The majority of previous studies that found decreases in urinary incontinence with weight loss focused on effects of large decreases in weight after bariatric surgery. The recent randomized study by Subak and colleagues is a significant addition to the literature because it indicates that even moderate weight loss, achievable with modifications in diet, exercise and behavior, can result in significant improvement in urinary incontinence in overweight and obese women. Importantly for clinicians, the investigators observed benefits of weight loss for stress, urge and mixed incontinence, suggesting that a weight loss program may be an initial strategy for many of their overweight and obese female patients with urinary incontinence.

Mary K. Townsend, ScD

Yerby Research Fellow, Department of Epidemiology
Harvard School of Public Health, Boston


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